Anti-SHBG (aa 41-140) polyclonal antibody

Species Reactivity

Human; Mouse; Rat

Immunogen

SHBG (NP_001031, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. The sequence is DPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGL RDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDS

Conjugate

Alternative Names

SHBG; sex hormone-binding globulin; ABP; SBP; TEBG; sex steroid-binding protein; testosterone-binding beta-globulin; testosterone-estrogen-binding globulin; testosterone-estradiol-binding globulin; testis-specific androgen-binding protein;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants.

Pathway

Nongenotropic Androgen signaling;