General Notes
This product (Catalog No. DPABH-22530) is a rabbit-derived polyclonal antibody raised against human SH3BP5, targeting the amino acid region 10–276 of the protein. It has been affinity purified by Protein A. SH3BP5 (SH3 Domain Binding Protein 5), also known as SAB, is a signaling protein that acts as a guanine nucleotide exchange factor (GEF) for RAB11 GTPases and a negative regulator of Bruton's tyrosine kinase (BTK). It plays a critical role in metabolic-immune crosstalk, specifically in mitochondrial respiration, JNK signaling, and B-cell malignancies.
DPABH-22530 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-22530 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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