Recombinant GST fusion protein corresponding to 171 amino acids of mouse Sh2b1. The sequence is ERWTHRFERLRLSRGGGTLKDGAGMIQREELLSFMGAEEAAPDPAGVGRGGGAAGLTSGG GGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSTITDVRTATALEMPDRE NTFVVKVEGPSEYILETSDALHVKAWVSDIQECLSPGPCPAISPRPMTLPH
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:1000. & The optimal working dilution should be determined by the end user.
Target
Alternative Names
SH2B1; SH2B adaptor protein 1; Psm; Irip; SH2-B; SH2-Bb; AI425885; Sh2bpsm1; mKIAA1299; C530001K22Rik; SH2B adapter protein 1; SH2 domain-containing protein 1B; SH2-B PH domain containing signaling mediator 1; pro-rich, PH and SH2 domain-containing signal
SH2B1 (SH2B adaptor protein 1) is a protein-coding gene. Diseases associated with SH2B1 include severe early-onset obesity-insulin resistance syndrome due to sh2b1 deficiency, and distal 16p11.2 microdeletion syndrome, and among its related super-pathways are Development Neurotrophin family signaling and Prolactin receptor signaling. GO annotations related to this gene include phospholipid binding and signal transducer activity. An important paralog of this gene is SH2B3.
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