This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Function
signal transducer activity;
Synonyms
SH2B1; SH2B adaptor protein 1; SH2B adapter protein 1; FLJ30542; SH2 B homolog; SH2B; SH2-B signaling protein; SH2 domain-containing protein 1B; SH2 domain-containing putative adapter SH2-B; pro-rich, PH and SH2 domain-containing signaling mediator; PSM; KIAA1299; DKFZp547G1110;
Citations
Publication ()
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