General Notes
This product (Catalog No. DPABH-15114) is a rabbit-derived polyclonal antibody raised against human SGK1, targeting the amino acid region 1–82 of the protein. This antibody exhibits cross-reactivity with Human SGK1 from mouse. It has been affinity purified by Protein A. Serum- and glucocorticoid-induced kinase 1 (SGK1),also named as SGK, is a S/T protein kinase that belongs to the AGC (cAMP-dependent, cGMP-dependent, and protein kinase C) kinase family. It is expressed in many cell types and participates in numerous cellular processes and it is ubiquitinated and degraded at the ER membrane(PMID: 16847254). The N-terminal motif of SGK1 is critical for its ubiquitination and degradation(PMID:16817852 ). SGK and Akt are likely to phosphorylate related substrates, as they share a similar consensus phosphorylation site (RXRXXS/T)(PMID:11154281). It has 5 isoforms produced by alternative promoter usage and alternative splicing.
DPABH-15114 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500), IF/ICC (1:200–1:400) applications.
DPABH-15114 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
Publication 
Loading ......
