Anti-SGK1 polyclonal antibody (DPABH-05721)

Rabbit anti-Human SGK1 (C-terminal) polyclonal antibody for WB, ICC/IF, IHC-P

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide, corresponding to 18 amino acids near the C-terminus of Human SGK1 (NP_005618).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 - 2 μg/ml; ICC/IF: 20 μg/ml; IHC-P: 5 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SGK1; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid regulated kinase; SGK; serine/threonine-protein kinase Sgk1; serine/threonine protein kinase SGK
Entrez Gene ID
UniProt ID

Product Background


Pathway
Aldosterone-regulated sodium reabsorption; Class I PI3K signaling events; FoxO family signaling; Glucocorticoid receptor regulatory network; IL-6 Signaling Pathway; Insulin Pathway;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Itani, OA; Liu, KZ; et al. Glucocorticoids stimulate human sgk1 gene expression by activation of a GRE in its 5 '-flanking region. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 283:E971-E979(2002).
Husted, RF; Lu, HY; et al. Oxygen regulation of the epithelial Na channel in the collecting duct. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 300:F412-F424(2011).

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