Specifications
Immunogen
A synthetic peptide of human SERPINI2 is used for rabbit immunization.
Target
Alternative Names
SERPINI2; serpin peptidase inhibitor, clade I (pancpin), member 2; PI14, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2 , serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2; serpin I2; MEPI; PANCPIN; pancpin
Product Background
Antigen Description
The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
Citations
Publication ()
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COA
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