Activity Accumulation and Cardiometabolic Risk in Youth: A Latent Profile Approach
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
Authors: Verswijveren, Simone J. J. M.; Lamb, Karen E.; Leech, Rebecca M.; Salmon, Jo; Timperio, Anna; Telford, Rohan M.; Mcnarry, Melitta A.; Mackintosh, Kelly A.; Daly, Robin M.; Dunstan, David W.; Hume, Clare; Cerin, Ester; Olive, Lisa S.; Ridgers, Nicola D.
Abstract
Introduction This cross-sectional study aimed to i) identify and characterize youth according to distinct physical activity (PA) and sedentary (SED) accumulation patterns, and ii) investigate associations of these derived patterns with cardiometabolic risk factors. Methods ActiGraph accelerometer data from 7- to 13-yr-olds from two studies were pooled (n= 1219; 843 (69%) with valid accelerometry included in analysis). Time accumulated in >= 5- and >= 10-min SED bouts, >= 1- and >= 5-min bouts of light, and >= 1-min bouts of moderate and vigorous PA was calculated. Frequency of breaks in SED was also obtained. Latent profile analysis was used to identify groups of participants based on their distinct accumulation patterns. Linear and logistic regression models were used to test associations of group accumulation patterns with cardiometabolic risk factors, including adiposity indicators, blood pressure, and lipids. Total PA and SED time were also compared between groups. Results Three distinct groups were identified: "prolonged sitters" had the most time in sustained SED bouts and the least time in vigorous PA bouts; "breakers" had the highest frequency of SED breaks and lowest engagement in sustained bouts across most PA intensities; and "prolonged movers" had the least time accumulated in SED bouts and the most in PA bouts across most intensities. Although breakers engaged in less time in PA bouts compared with other groups, they had the healthiest adiposity indicators. No associations with the remaining cardiometabolic risk factors were found. Conclusion Youth accumulate their daily activity in three distinct patterns (prolonged sitters, breakers, and prolonger movers), with those breaking up sitting and least time in prolonged PA bouts across the day having a lower adiposity risk. No relationships with other cardiometabolic risk factors were identified.
Should we pay more attention to low creatinine levels?
ENDOCRINOLOGIA DIABETES Y NUTRICION
Authors: Amado Diago, Carlos A.; Amado Senaris, Jose A.
Abstract
A review is made of the basic aspects of creatine/creatinine metabolism and the close relationship between creatinine and muscle mass, which makes the former a biochemical marker of the latter. Emphasis is placed on the current prognostic value of both the low urinary excretion of creatinine and low serum creatinine levels in different clinical settings in which sarcopenia probably plays a significant role in morbidity and mortality. (c) 2020 SEEN y SED. Published by Elsevier Espana, S.L.U. All rights reserved.