Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Recombinant fragment within Human SEC61A aa 350-450. The exact sequence is proprietary.Database link: Q9H9S3
Applications
Application Notes
ICC/IF: 1/250; Flow Cyt: 1/100; IP: 1/40 - 1/60; IHC-P: 1/50 - 1/100; WB: 1/1000 - 1/10000.
Target
Alternative Names
SEC61A1; Sec61 alpha 1 subunit (S. cerevisiae); protein transport protein Sec61 subunit alpha isoform 1; Sec61 alpha-1; sec61 homolog; protein transport protein SEC61 alpha subunit; protein transport protein Sec61 subunit alpha; SEC61; HSEC61; SEC61A;
Product Background
Antigen Description
Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.
Pathway
Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; ER-Phagosome pathway, organism-specific biosystem; Gene Expression, organism-specific biosystem; Immune System, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-7532 in a publication?
Let us know and earn a reward for your research.