Synthetic peptide corresponding to a region derived from internal residues of human sodium channel, voltage-gated, type II, alpha subunit
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:25-1:100
General Notes
This product (Catalog No. DPABH-26096) is a rabbit-derived IgG polyclonal antibody raised against human SCN2A. This antibody exhibits cross-reactivity with SCN2A from rat. It has been affinity purified by protein A. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. Allelic variants of this gene are associated with seizure disorders and autism spectrum disorder. Alternative splicing results in multiple transcript variants. DPABH-26096 is suitable for use in IHC (1:25–1:100) application. DPABH-26096 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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