General Notes
This product (Catalog No. DPABH-22143) is a rabbit-derived polyclonal antibody raised against human SAP30. This antibody exhibits cross-reactivity with SAP30 from mouse. It has been affinity purified by Protein A. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
DPABH-22143 is suitable for use in IHC 1 (50-1:200), WB 1 (1000-3000) applications.
DPABH-22143 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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