General Notes
This product (Catalog No. DPABH-28869) is a rabbit-derived IgG polyclonal antibody raised against human S1PR5. It has been affinity purified by protein A. The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.
DPABH-28869 is suitable for use in Western blot (WB) (1:500–1:1,000) application.
DPABH-28869 is supplied as a liquid formulation in PBS with 0.01% thimerosal, 50% glycerol, pH7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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