Fusion protein corresponding to residues near the N terminal of human S100 calcium binding protein A1
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:25-1:100
General Notes
This product (Catalog No. DPABH-00160) is a rabbit-derived IgG polyclonal antibody raised against human S100A1. It has been affinity purified by protein A. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. DPABH-00160 is suitable for use in IHC (1:25–1:100) application. DPABH-00160 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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