Specifications
Species Reactivity
Bovine
Immunogen
Purified bovine brain S100 protein
Target
Alternative Names
S100A1; S100 calcium binding protein A1; protein S100-A1; MGC159706;
Product Background
Antigen Description
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
Citations
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Paus, E; Haugen, MH; et al. TD-11 workshop report: characterization of monoclonal antibodies to S100 proteins. TUMOR BIOLOGY 32:1-12(2011).
Muramatsu, Y; Kamegai, A; et al. Novel Ca2+-binding S100 proteins, glial fibrillary acidic protein and tenascin in chondro-osseous tumors. ACTA HISTOCHEMICA ET CYTOCHEMICA 30:445-453(1997).
COA
Certificate of Analysis
