Rabbit Anti-Human RAD51C (center) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RAD51C.

Conjugate

Application Notes

WB: 1:500-1:1000
IHC: 1:100-1:200
IF/ICC: 1:100-1:500

General Notes

This product (Catalog No. DPABH-21825) is a rabbit-derived polyclonal antibody raised against human RAD51C. It has been affinity purified by Protein A. This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.
DPABH-21825 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:100–1:200), IF/ICC (1:100–1:500) applications.
DPABH-21825 is supplied as a liquid formulation in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

RAD51L2; DNA repair protein RAD51 homolog 3; R51H3; RAD51 homolog C; RAD51-like protein 2

Entrez Gene ID

UniProt ID