Anti-RAD51 (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Chicken; Human

Immunogen

Recombinant full length protein corresponding to Human Rad51 aa 1-339.Sequence: MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVE AVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEII QITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDR GGGEGKAMYIDTEGTFRPERLL

Conjugate

Application Notes

WB: 1/1000 - 1/10000; ICC/IF: 1/1000 - 1/10000. Dot Blot: 1/1000 - 1/5000; Indirect ELISA: 1/2000 - 1/5000.

Alternative Names

RAD51; RAD51 recombinase; RECA; BRCC5; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930; DNA repair protein RAD51 homolog 1; RAD51 homolog A; RecA-like protein; recombination protein A; RecA, E. coli, homolog of; BRCA1/BRCA2-containing complex, subunit 5;

Entrez Gene ID

UniProt ID

Antigen Description

Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.

Pathway

Assembly of the RAD51-ssDNA nucleoprotein complex; BARD1 signaling events; DNA Repair; Double-Strand Break Repair; Fanconi anemia pathway; Homologous DNA pairing and strand exchange;