Specifications
Immunogen
Full length Human recombinant Human RUNX1T1/ ETO (NP_783553), produced in HEK293T cells.
Applications
Application Notes
Flow Cyt: 1/50; WB: 1/2000; ICC/IF: 1/100.
Target
Alternative Names
RUNX1T1; runt-related transcription factor 1; translocated to, 1 (cyclin D-related); AML1T1, CBFA2T1, core binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D related; protein CBFA2T1; CDR; ETO; MTG8; ZMYND2; eight twenty one prote
Product Background
Antigen Description
Transcription regulator that excerts its function by binding to histone deacetylases and transcription factors. Can repress transactivation mediated by TCF12.
Pathway
Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Pathways in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
Citations
Publication ()
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