Specifications
Immunogen
A synthetic peptide of human RSAD2 is used for rabbit immunization.
Target
Alternative Names
RSAD2; radical S-adenosyl methionine domain containing 2; radical S-adenosyl methionine domain-containing protein 2; cig5; vig1; viperin; cytomegalovirus-induced gene 5 protein; virus inhibitory protein, endoplasmic reticulum-associated, interferon-induci
Product Background
Antigen Description
Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.
Pathway
Influenza A, organism-specific biosystem; Influenza A, conserved biosystem;
Citations
Publication ()
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