Anti-RSAD2 monoclonal antibody, clone NbQ.WJQ

Antibody Isotype

IgG2a

Clone

NbQ.WJQ

Species Reactivity

Mouse; Human

Immunogen

Recombinant fragment corresponding to amino acids 92-362 of Mouse Viperin

Conjugate

Alternative Names

RSAD2; radical S-adenosyl methionine domain containing 2; radical S-adenosyl methionine domain-containing protein 2; viperin; VHSV-induced-like protein; viral hemorrhagic septicemia virus (VHSV)-induced gene 1; virus inhibitory protein, endoplasmic reticu

Entrez Gene ID

UniProt ID

Antigen Description

Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.

Pathway

Influenza A, organism-specific biosystem; Influenza A, conserved biosystem;