Anti-RPS6KA3 monoclonal antibody

Antibody Isotype

IgG2b

Species Reactivity

Mouse; Human

Immunogen

Recombinant fragment: PLAQLADPWQ KMAVESPSDS AENGQQIMDE PMGEEEINPQ TEEVSIKEIA ITHHVKEGHE KADPSQFELL KVLGQGSFGK VFLVKKISGS DARQ, corresponding to amino acids 2-95 (NP_004577) of Human Rsk 2/ MAPKAP Kinase 1b with a 26kDa tag.

Conjugate

Application Notes

WB: 1 - 5 μg/ml;

Alternative Names

RPS6KA3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; CLS, Coffin Lowry syndrome , mental retardation, X linked 19 , MRX19, ribosomal protein S6 kinase, 90kD, polypeptide 3; ribosomal protein S6 kinase alpha-3; HU 3; RSK; RSK2; RSK-2; p90-RSK 3;

Entrez Gene ID

UniProt ID

Antigen Description

Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.

Pathway

Activated TLR4 signalling, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Axon guidance, organism-specific biosystem; CREB phosphorylation, organism-specific biosystem; CREB phosphorylation through the activation of Ras, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; Cytoplasmic Ribosomal Proteins, organism-specific biosystem;