Anti-RPS3A monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Mouse; Rat; Human

Immunogen

A synthetic peptide of human RPS3A is used for rabbit immunization.

Conjugate

Alternative Names

RPS3A; ribosomal protein S3A; S3A; FTE1; MFTL; 40S ribosomal protein S3a; fte-1; v-fos transformation effector protein 1;

Entrez Gene ID

UniProt ID

Antigen Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S3AE family of ribosomal proteins. It is located in the cytoplasm. Disruption of the gene encoding rat ribosomal protein S3a, also named v-fos transformation effector protein, in v-fos-transformed rat cells results in reversion of the transformed phenotype. This gene is co-transcribed with the U73A and U73B small nucleolar RNA genes, which are located in its fourth and third introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants have been found for this gene.

Pathway

Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S; Cap-dependent Translation Initiation; Cytoplasmic Ribosomal Proteins; Disease; Eukaryotic Translation Termination; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; GTP hydrolysis and joining of the 60S ribosomal subunit; Gene Expression; Influenza Infection; Influenza Life Cycle;