Synthetic peptide within Human RPL35 aa 85-115 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: P42766
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/10 - 1/50; WB: 1/100 - 1/500;
Target
Alternative Names
RPL35; ribosomal protein L35; L35; 60S ribosomal protein L35;
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
Pathway
Cap-dependent Translation Initiation; Disease; Eukaryotic Translation Initiation; Formation of a pool of free 40S subunits
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Lebrun, SJ; Petchpud, W; et al. Development of a protein microarray library and a system for rheumatoid-arthritis disease marker screening. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY 42:151-155(2005).
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