General Notes
This product (Catalog No. DPABH-16037) is a rabbit-derived polyclonal antibody raised against human RPL35, targeting the amino acid region 1–123 of the protein. This antibody exhibits cross-reactivity with Human RPL35 from mouse and rat. It has been affinity purified by Protein A. This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
DPABH-16037 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:500–1:2,000), IF/ICC (1:50–1:500) applications.
DPABH-16037 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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