Anti-RNF40 (aa 102-200) polyclonal antibody

Species Reactivity

Human

Immunogen

RNF40 (NP_055586, 102 a.a. ~ 200 a.a) partial recombinant protein with GST tag. The sequence is DETVEALLRCHESQGELSSAPEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEP ALAFVVALGASSSEEVELELQGRMEFSKAAVSRVVEASD

Conjugate

Alternative Names

RNF40; ring finger protein 40, E3 ubiquitin protein ligase; BRE1B; RBP95; STARING; E3 ubiquitin-protein ligase BRE1B; BRE1-B; Rb-associated protein; BRE1 E3 ubiquitin ligase homolog B; 95 kDa retinoblastoma-associated protein; 95 kDa retinoblastoma protei

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.