Anti-RNF144B monoclonal antibody (DCABH-413)

Mouse anti-Human RNF144B monoclonal antibody for WB, FC, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
7C22
Species Reactivity
Human
Immunogen
Recombinant full length Human IBRDC2 produced in HEK293T cells (NP_877434).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500; Flow Cyt: 1/100; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
RNF144B; ring finger protein 144B; IBR domain containing 2 , IBRDC2; E3 ubiquitin-protein ligase RNF144B; bA528A10.3; IBR domain containing 2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Immune System, organism-specific biosystem;

Citations


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References


Taebunpakul, P; Sayan, BS; et al. Apoptin induces apoptosis by changing the equilibrium between the stability of TAp73 and Delta Np73 isoforms through ubiquitin ligase PIR2. APOPTOSIS 17:762-776(2012).
Conforti, F; Yang, AL; et al. PIR2/Rnf144B regulates epithelial homeostasis by mediating degradation of p21WAF1 and p63. ONCOGENE 32:4758-4765(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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