Specifications
Immunogen
Recombinant full length Human RND1 produced in HEK293T cells (NP_055285).
Applications
Application Notes
WB: 1/2000; Flow Cyt: 1/100; ICC/IF: 1/100;
Target
Alternative Names
RND1; Rho family GTPase 1; rho-related GTP-binding protein Rho6; ARHS; ras homolog gene family; member S; Rho6; RHOS; GTP-binding protein; ras homolog gene family, member S; RHO6; FLJ42294;
Product Background
Antigen Description
Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
Pathway
Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Developmental Biology, organism-specific biosystem; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion, organism-specific biosystem; Sema4D in semaphorin signaling, organism-specific biosystem; Sema4D induced cell migration and growth-cone collapse, organism-specific biosystem.
Citations
Publication ()
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COA
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