Synthetic peptide corresponding to a region within C terminal amino acids 183-232 (ASMLCLNKPS PLPQKSPVRS LSKRLLHLPS RSELISSTFK KEKAKSCSIM) of Human RND1 (NP_055285).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
RND1; Rho family GTPase 1; rho-related GTP-binding protein Rho6; ARHS; ras homolog gene family; member S; Rho6; RHOS; GTP-binding protein; ras homolog gene family, member S; RHO6; FLJ42294;
Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
Pathway
Axon guidance; Developmental Biology; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Sema4D in semaphorin signaling; Sema4D induced cell migration and growth-cone collapse;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Oinuma, I; Katoh, H; et al. Molecular dissection of the semaphorin 4D receptor Plexin-B1-stimulated R-Ras GTPase-activating protein activity and neurite remodeling in hippocampal neurons. JOURNAL OF NEUROSCIENCE 24:11473-11480(2004).
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COA
Certificate of Analysis