RNASEL (NP_066956, 619 a.a. ~ 728 a.a) partial recombinant protein with GST tag. The sequence is QPGPSEHSKSFDKWTTKINECVMKKMNKFYEKRGNFYQNTVGDLLKFIRNLGEHIDEEKH KKMKLKIGDPSLYFQKTFPDLVIYVYTKLQNTEYRKHFPQTHSPNKPQCD
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.
Pathway
Cytokine Signaling in Immune system; Hepatitis C; Herpes simplex infection; Influenza A
Citations
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