Anti-RIPK1 monoclonal antibody (DCABH-9538) Knockout Validated

Mouse anti-Human RIPK1 monoclonal antibody for FC, WB, IP

Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
8I21
Species Reactivity
Mouse, Rat, Human
Immunogen
Recombinant full length human RIP protein purified from E.coli (His/ABD-RIP)
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 1/50 - 1/100; WB: 1/500 - 1/2000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
RIPK1; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor-interacting serine/threonine-protein kinase 1; RIP; RIP-1; cell death protein RIP
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of Pro-Caspase 8, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis Modulation by HSP70, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket
Mouse IgG2b Isotype Control DAGIC1236 FC EIA WB Mouse PDF Inquiry

References


Voigt, S; Philipp, S; et al. TRAIL-induced programmed necrosis as a novel approach to eliminate tumor cells. BMC CANCER 14:-(2014).
Mannam, VKR; Lewis, RE; et al. The fate of renal allografts hinges on responses of the microvascular endothelium. EXPERIMENTAL AND MOLECULAR PATHOLOGY 94:398-411(2013).

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