Anti-RIPK1 monoclonal antibody (DCABH-2582)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
3E7
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 133-422 of Human RIP produced in E.coli (NP_003795).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; IHC-P: 1/150; Flow Cyt: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
RIPK1; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor-interacting serine/threonine-protein kinase 1; RIP; RIP-1; cell death protein RIP
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of Pro-Caspase 8, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis Modulation by HSP70, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Voigt, S; Philipp, S; et al. TRAIL-induced programmed necrosis as a novel approach to eliminate tumor cells. BMC CANCER 14:-(2014).
Mannam, VKR; Lewis, RE; et al. The fate of renal allografts hinges on responses of the microvascular endothelium. EXPERIMENTAL AND MOLECULAR PATHOLOGY 94:398-411(2013).

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