Anti-RFT1 (aa 211-320) polyclonal antibody

Species Reactivity

Human

Immunogen

RFT1 (NP_443091, 211 a.a. ~ 320 a.a) partial recombinant protein with GST tag. The sequence is TKLQTLPVSRITDLLPNITRNGAFINWKEAKLTWSFFKQSFLKQILTEGERYVMTFLNVL NFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLERGKDATLQKQE

Conjugate

Alternative Names

RFT1; RFT1 homolog (S. cerevisiae); CDG1N; protein RFT1 homolog; RFT1, requiring fifty three 1 homolog; congenital disorder of glycosylation 1N; putative endoplasmic reticulum multispan transmembrane protein;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type In.[provided by RefSeq, Dec 2008]

Pathway

Asparagine N-linked glycosylation; Metabolism of proteins; N-Glycan biosynthesis;