Specifications
Immunogen
A synthetic peptide of human RFT1 is used for rabbit immunization.
Target
Alternative Names
RFT1; RFT1 homolog (S. cerevisiae); RFT1, requiring fifty three 1 homolog (S. cerevisiae); protein RFT1 homolog; RFT1, requiring fifty three 1 homolog; putative endoplasmic reticulum multispan transmembrane protein; CDG1N; FLJ25945; DKFZp667J092;
Product Background
Antigen Description
This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type In
Pathway
Asparagine N-linked glycosylation, organism-specific biosystem; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; N-Glycan biosynthesis, organism-specific biosystem; N-Glycan biosynthesis, conserved biosystem; Post-translational protein modification, organism-specific biosystem.
Citations
Publication ()
Have you cited DCABH-13232 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
