Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Pathway
DNA Damage Bypass; DNA Repair; Fanconi anemia pathway; Translesion synthesis by DNA polymerases bypassing lesion on DNA template; Translesion synthesis by HREV1;
Citations
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