A synthetic peptide of human RECK is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
RECK; reversion-inducing-cysteine-rich protein with kazal motifs; ST15; reversion-inducing cysteine-rich protein with Kazal motifs; suppressor of tumorigenicity 15 protein; membrane-anchored glycoprotein (metastasis and invasion); suppression of tumorigen
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.
Pathway
MicroRNAs in cancer.
Citations
Publication ()
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