RAMP3 (receptor calcitonin activity modifying protein 3) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. It acts as a receptor for adrenomedullin (AM) together with CALCRL. It is strongly expressed in lung, breast, immune system and fetal tissues and belongs to the RAMP family.
Pathway
Calcitonin-like ligand receptors; Class B/2 (Secretin family receptors); G alpha (s) signalling events; GPCR downstream signaling; GPCR ligand binding; Myometrial Relaxation and Contraction Pathways; Signal Transduction
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