Full length protein, corresponding to amino acids 1-752 of Human PTPN22 Isoform 3 (AAH71670.1).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
PTPN22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non receptor type 8; PTPN8; tyrosine-protein phosphatase non-receptor type 22; Lyp; Lyp1; Lyp2; lymphoid phosphatase; PEST-domain phosphatase; lymphoid-sp
Seems to act on Cbl. May play a role in regulating the function of Cbl and its associated protein kinases. Acts as negative regulator of T cell receptor (TCR) signaling. Dephosphorylates and inactivates the SRC family kinases.
Pathway
T Cell Receptor Signaling Pathway;
Citations
Publication ()
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COA
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