Anti-PTH1R monoclonal antibody (DCABH-8596)

Mouse anti-Human PTH1R monoclonal antibody for IHC-P, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4E2.2
Species Reactivity
Rabbit, Human
Immunogen
A 23 amino acid peptide of the hPTH/ PTHrP receptor.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 2 - 4 μg/ml; WB: 1 - 2 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PTH1R; parathyroid hormone 1 receptor; parathyroid hormone receptor 1 , PTHR, PTHR1; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH1 receptor; PTH/PTHr receptor
Entrez Gene ID
UniProt ID

Product Background


Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;

Citations


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References


Zhu, J; Siclari, VA; et al. Amphiregulin-EGFR Signaling Mediates the Migration of Bone Marrow Mesenchymal Progenitors toward PTH-Stimulated Osteoblasts and Osteocytes. PLOS ONE 7:-(2012).
Song, GJ; Fiaschi-Taesch, N; et al. Endogenous Parathyroid Hormone-Related Protein Regulates the Expression of PTH Type 1 Receptor and Proliferation of Vascular Smooth Muscle Cells. MOLECULAR ENDOCRINOLOGY 23:1681-1690(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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