Recombinant human PSMF1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 122-271 aa of BC029836
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:1000 IHC: 1:50-1:500
General Notes
This product (Catalog No. DPABH-02350) is a rabbit-derived polyclonal antibody raised against human PSMF1, targeting the amino acid region 122–271 of the protein. This antibody exhibits cross-reactivity with Human PSMF1 from mouse and rat. It has been affinity purified by Protein A. PSMF1 is also named as PI31(proteasome (prosome, macropain) inhibitor subunit 1) and belongs to proteasome inhibitor PI31 family. PI31, which localizes at the nuclear envelope/endoplasmic reticulum membrane, acts as a selective modulator of the proteasome-mediated steps in MHC class I antigen processing(PMID:18495667). PI31 does not inhibit cell-surface transport of glycoproteins in general and it may serve to control immunoproteasome formation and may thereby maintain an intracellular balance between constitutive and immunoproteasomes(PMID:12374861). DPABH-02350 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500) applications. DPABH-02350 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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