Anti-PSME4 monoclonal antibody, clone FQS24688(C)

Antibody Isotype

IgG

Clone

FQS24688(C)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Proteasome Activator Subunit 4 aa 1750 to the C-terminus. The exact sequence is proprietary.Database link: Q14997

Conjugate

Application Notes

WB: 1/1000; IHC-P: 1/50 - 1/100; ICC/IF: 1/50 - 1/100; Flow Cyt: 1/110;

Alternative Names

PSME4; proteasome (prosome, macropain) activator subunit 4; proteasome activator complex subunit 4; KIAA0077; PA200; proteasome activator PA200; proteasome activator 200 kDa; FLJ21864; MGC138374; MGC142228;

Entrez Gene ID

UniProt ID

Antigen Description

Activates proteasomal cleavage of peptides in an energy-independent manner. May be involved in spermatogenesis. May be involved in DNA repair.

Pathway

APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem;