Anti-PSME4 monoclonal antibody, clone FQS24687(C)

Antibody Isotype

IgG

Clone

FQS24687(C)

Species Reactivity

Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Proteasome Activator Subunit 4 aa 1-100. The exact sequence is proprietary.Database link: Q14997

Conjugate

Application Notes

Flow Cyt: 1/210; WB: 1/1000 - 1/10000.

Alternative Names

PSME4; proteasome (prosome, macropain) activator subunit 4; proteasome activator complex subunit 4; KIAA0077; PA200; proteasome activator PA200; proteasome activator 200 kDa; FLJ21864; MGC138374; MGC142228;

Entrez Gene ID

UniProt ID

Antigen Description

Activates proteasomal cleavage of peptides in an energy-independent manner. May be involved in spermatogenesis. May be involved in DNA repair.

Pathway

APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc2 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc2 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc2 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc2 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem.