This product (Catalog No. DPABH-00146) is a rabbit-derived polyclonal antibody raised against human PRSS1. This antibody exhibits cross-reactivity with PRSS1 from mouse. It has been affinity purified by Protein A. This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. DPABH-00146 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:100–1:200) applications. DPABH-00146 is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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