PRRX2 (NP_057391, 110 a.a. ~ 202 a.a) partial recombinant protein with GST tag. The sequence is TFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLAS RSASLLKSYSQEAAIEQPVAPRPTALSPDYLSW
Conjugate
Unconjugated
Target
Alternative Names
PRRX2; paired related homeobox 2; PMX2; PRX2; paired mesoderm homeobox protein 2; PRX-2; paired-related homeobox protein 2; paired-like homeodomain protein PRX2;
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
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