Anti-PROP1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PROP1 is used for rabbit immunization.

Conjugate

Alternative Names

PROP1; PROP paired-like homeobox 1; prophet of Pit1, paired like homeodomain transcription factor; homeobox protein prophet of Pit-1; pituitary-specific homeodomain factor; prophet of Pit1, paired-like homeodomain transcription factor; CPHD2; PROP-1;

Entrez Gene ID

UniProt ID

Antigen Description

PROP1 has both DNA-binding and transcriptional activation ability. Its expression leads to ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes, and caudomedial thyrotropes. Inactivating mutations in PROP1 result in deficiencies of luteinizing hormone (LH; MIM 152780), follicle-stimulating hormone (FSH; MIM 136530), growth hormone (GH; MIM 139250), prolactin (PRL; MIM 176760), and thyroid-stimulating hormone (TSH; MIM 188540). See combined pituitary hormone deficiency (CPHD; MIM 262600).