Anti-PRMT2 (aa 118-131) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide: DQPRTTKYHSVILQ with a Cysteine residue linker, corresponding to internal sequence amino acids 118-131 of Human PRMT2.

Conjugate

Application Notes

WB: 1 - 3 μg/ml.

Alternative Names

PRMT2; protein arginine methyltransferase 2; HMT1 (hnRNP methyltransferase, S. cerevisiae) like 1; HMT1 hnRNP methyltransferase like 1 (S. cerevisiae); HRMT1L1; protein arginine N-methyltransferase 2; MGC111373; PRMT2 beta; PRMT2 alpha; PRMT2 gamma; HMT1

Entrez Gene ID

UniProt ID

Antigen Description

Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.

Pathway

mRNA processing;