General Notes
This product (Catalog No. DPABH-01794) is a rabbit-derived polyclonal antibody raised against human PRKCSH, targeting the amino acid region 401–511 of the protein. It has been affinity purified by Protein A. PRKCSH (also known as protein kinase C substrate 80K-H) is a protein-coding gene located on human chromosome 19p13.2 that encodes the noncatalytic beta subunit of glucosidase II, an enzyme complex essential for the processing of N-linked glycoproteins in the endoplasmic reticulum (ER). This subunit, also known as hepatocystin or GIIβ, facilitates the removal of glucose residues from nascent polypeptides, aiding in proper protein folding, quality control, and ER-associated degradation (ERAD). Mutations in PRKCSH are associated with autosomal dominant polycystic liver disease (PCLD), a condition characterized by multiple fluid-filled cysts in the liver, often without renal involvement.
DPABH-01794 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-01794 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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