Specifications
Immunogen
A synthetic peptide of human PRKCSH is used for rabbit immunization.
Target
Alternative Names
PRKCSH; protein kinase C substrate 80K-H; G19P1; glucosidase 2 subunit beta; hepatocystin; AGE-binding receptor 2; glucosidase II subunit beta; glucosidase II, beta subunit; protein kinase C substrate, 80 Kda protein; protein kinase C substrate 60.1 kDa p
Product Background
Antigen Description
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease (PCLD). Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Pathway
Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; Calnexin/calreticulin cycle, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; N-glycan trimming in the ER and Calnexin/Calreticulin cycle, organism-specific biosystem;
Citations
Publication ()
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