Anti-PRKAR1A monoclonal antibody (DCABH-676)

Mouse anti-Human PRKAR1A monoclonal antibody for WB, IHC-P, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
7D8
Species Reactivity
Human
Immunogen
Recombinant Human Protein Kinase A regulatory subunit I alpha protein expressed in 293T cells.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; IHC-P: 1/50; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PRKAR1A; protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1); PRKAR1, TSE1; cAMP-dependent protein kinase type I-alpha regulatory subunit; tissue-specific extinguisher 1; protein kinase A type 1a regulatory subunit
Entrez Gene ID
UniProt ID

Product Background


Pathway
Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Aquaporin-mediated transport, organism-specific biosystem; Ca-dependent events, organism-specific biosystem; CaM pathway, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calmodulin induced events, organism-specific biosystem;

Citations


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References


Zembowicz, A; Knoepp, SM; et al. Loss of expression of protein kinase A regulatory subunit 1 alpha in pigmented epithelioid melanocytoma but not in melanoma or other melanocytic lesions. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 31:1764-1775(2007).
Tadjine, M; Lampron, A; et al. Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD). CLINICAL ENDOCRINOLOGY 69:367-373(2008).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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