Specifications
Immunogen
Synthetic phosphopeptide, conjugated to KLH, corresponding to amino acids 193-202 of Human PKA beta (catalytic subunit) with phosphoThr at position 198 (NP_002722.1).
Applications
Application Notes
ELISA: 1/1 - 1/1000; IHC-P: 5 μg/ml.
Target
Alternative Names
PRKACB; protein kinase, cAMP-dependent, catalytic, beta; PKACB; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; protein kinase A catalytic subunit beta; cAMP-dependent protein kinase catalytic beta subunit isoform 4ab;
Product Background
Antigen Description
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.
Pathway
AMPK signaling; Adaptive Immune System; Adrenergic signaling in cardiomyocytes; Amoebiasis
Citations
Publication ()
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COA
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