Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.
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Q: Can you provide information on the species reactivity of the Anti-PPP1R16B monoclonal antibody, clone FQS21304(C)?
A: Anti-PPP1R16B monoclonal antibody, clone FQS21304(C) are typically raised against Human PPP1R16B antigens.
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