Anti-PPM1G (aa 462-544) polyclonal antibody

Species Reactivity

Human

Immunogen

PPM1G (NP_817092, 462 a.a. ~ 544 a.a) partial recombinant protein with GST tag. The sequence is QRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRK LEEVLSTEGAEENGNSDKKKKAK

Conjugate

Alternative Names

PPM1G; protein phosphatase, Mg2+/Mn2+ dependent, 1G; PP2CG; PPP2CG; PP2CGAMMA; protein phosphatase 1G; PP2C-gamma; PP2C, gamma; protein phosphatase 1C; protein phosphatase 2C gamma isoform; protein phosphatase 2C isoform gamma; protein phosphatase magnesi

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.

Pathway

mRNA processing;